Menopause support supplements

The menopause journey is one of profound change – physically, mentally, and emotionally. But you don’t have to walk it alone. With the right nutrients, plant extracts, and care, you can navigate this transition with more calm, confidence, and inner balance.

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  • Menopause
    Biogena, Nutrifem Agnubalance®, Bottle, white, For supporting the hormonal balance of women®

    Biogena Essentials

    Nutrifem Agnubalance®

    Supports your wellbeing during the menopause

    €32.90
  • Bestseller
    Biogena, Osteo Calbon Komplex®, Bottle, white, Premium preparation for maintaining strong bone structures®

    Biogena Exceptionals

    Osteo Calbon Complex® Gold

    Premium bone and joint complex with calcium, vitamin D & more

    €39.90
  • Biogena Aesthetics, KOLLAGEN PULVER+, Sachet, magenta, PURE SCIENCE. EXCEPTIONAL GLOW.

    Biogena AESTHETICS

    Marine Collagen Powder +

    Collagen powder - hydrolyzate with glycine, biotin, zinc & valuable plant extracts - delicious cherry-thyme flavor

    €69.90
  • Menopause
    Biogena, Yams Balance, Bottle, white, With 16% diosgenin

    Biogena Essentials

    Yams Balance

    Targeted diosgenin support during hormonal shifts – powered by the strength of wild yam.

    €39.90
  • Marine Collagen Powder+ Neutral

    Biogena AESTHETICS

    Marine Collagen Powder+ Neutral

    Unflavoured Collagen Powder – with Biotin & Zinc to Support Beautiful Skin*

    €34.90
  • Marine Collagen Powder +

    Biogena AESTHETICS

    Marine Collagen Powder +

    Collagen powder - hydrolyzate with glycine, biotin, zinc & valuable plant extracts - delicious cherry-thyme flavor

    €34.90
  • Biogena, Vitamin B₆ aktiviert P5P, Bottle, white, Pyridoxal-5’-Phosphat

    Biogena Essentials

    Vitamin B6 activated P5P

    Vitamin B6 as active P5P – optimally available for metabolism

    €25.90

Best vitamins, minerals and plant extracts for menopause: what does your body need right now?

As your hormones shift gears, things can feel a little off – hot flashes, mood swings, sleepless nights, and more. But here’s the good news: there are gentle, natural ways to bring more ease into this new phase. Alongside a positive mindset and regular movement, specific vitamins, minerals, and botanicals can help guide your body through change – and back to balance.

B Vitamins – your daily go-to for hormone balance & vitality

B vitamins are lifelong allies for women. Why? Because they support your nervous system, help you stay mentally sharp, fuel your energy metabolism, and play a crucial role in how you cope with stress. They’re also key players in hormone production.

Three B vitamins really shine during menopause:

Vitamin B5 – your stress soother

Fatigue, restlessness, feeling less resilient – it’s all part of the hormonal rollercoaster. Vitamin B5 helps your body produce stress hormones and can support you in staying grounded through turbulent times.

Vitamin B6 – the emotional balancer

Feeling emotionally out of sync? You’re not alone. Vitamin B6 supports the production of serotonin (your “feel-good” neurotransmitter) and melatonin (the sleep hormone), helping bring calm and better sleep. It also plays a key role in regulating estrogen, progesterone, and androgen levels – especially important if estrogen dominance is throwing you off.

Science-backed mood support with B vitamins

Research suggests that supplementing with high-dose B vitamins can lift mood and ease tension – especially when a deficiency is present. A simple, natural way to reclaim your emotional balance.

Vitamin B9 (Folic Acid) – your cool-down companion

Hot flashes? You’re in good company—about 75% of women experience them. A 2013 study found that folic acid may help reduce their frequency and intensity. Bonus: Vitamin B9 also supports mood stability during hormonal changes.

Vitamin E – your antioxidant shield

As estrogen levels drop, oxidative stress increases—and that can make menopause symptoms feel even more intense. Vitamin E, a powerful antioxidant, helps protect your cells from damage and supports healthy fatty acids like omega-3.

It may even help reduce the severity of hot flashes. Protection that feels like a warm hug from within.

Vitamin D – your menopause must-have

This sunshine vitamin is essential at every age—but it’s especially important now. It contributes to strong bones, muscles, and immune function, supports mood, and plays a role in hormone regulation.

And there’s more: Vitamin D may support urogenital and sexual health after menopause, helping ease symptoms like dryness, irritation, or discomfort—and reducing the risk of urinary tract infections.

Health Insight: Vitamin D & Hashimoto’s – a crucial connection

Hashimoto’s thyroiditis is especially common among women in midlife—and it often goes hand in hand with low vitamin D levels. Here’s why:

  • Your body may struggle to metabolize vitamin D efficiently

  • Changes in vitamin D receptors can reduce its effectiveness

  • Chronic inflammation increases demand

The fix? Targeted supplementation. Studies show that vitamin D can help reduce antibody levels in people with Hashimoto’s. A valuable step in supporting thyroid health.

Wild Yam – for inner harmony

Used for centuries in traditional herbal medicine, wild yam contains diosgenin—a plant compound similar to progesterone. It's often recommended to help gently counterbalance estrogen dominance, making it a powerful botanical for midlife women seeking more hormonal ease.

Vitex (Chasteberry) – a natural way to support hormone health

Vitex is a trusted botanical that supports hormonal harmony by encouraging progesterone production and helping regulate prolactin levels. That means it can gently support your body in recalibrating the estrogen–progesterone balance—an important part of easing into menopause with grace.

Collagen & Hyaluronic Acid – beauty support from the inside out

As estrogen levels decline, your skin can change noticeably—losing firmness, moisture, and elasticity. The reason? Your body produces less collagen, elastin, and hyaluronic acid. But with the right nutrients, you can support your skin’s natural glow from within.

Collagen peptides and hyaluronic acid help restore bounce, hydration, and smoothness—giving your skin exactly what it needs during this time of change.

Menopause supplements: Find what fits your life

Looking for ways to support your body during menopause? We offer high-quality supplements in formats that work for you:

  • Capsules: Easy, convenient, and free from unnecessary additives—especially when made following our Reinsubstanzenprinzip.

  • Tablets: Also convenient, but be sure to check the label—tablets often contain more fillers than capsules.

  • Liquids (drops, sprays, or drinks): Great for those who prefer not to swallow pills. Just make sure you choose clean formulas without added extras.

Whatever format you choose, make sure it matches your lifestyle—and always opt for quality over quantity.

BIOGENA’s Menopause Essentials – a closer look

Biogena, Nutrifem Agnubalance®, Bottle, white, For supporting the hormonal balance of women®Nutrifem Agnubalance®Biogena, Osteo Calbon Komplex®, Bottle, white, Premium preparation for maintaining strong bone structures®Osteo Calbon Complex® GoldMarine Collagen Powder +Marine Collagen Powder +
Price€32.90€39.90€34.90
Info

Active ingredient composition to support hormonal balance in women

Premium Bone Complex based on the latest scientific findings

Fruity collagen drink - designed to make your skin glow from within

Properties
  • With valuable extracts of monk's pepper, hops, soya and yam

  • With vitamin B6 to support hormonal balance

  • For menopausal symptoms such as hot flushes, sweating or restlessness

  • Hormone-free

  • With the most important nutrients for maintaining strong bone structures

  • Calcium and phosphorus in a natural form

  • With vitamin D3 for the absorption and utilisation of calcium and phosphorus

  • Clinically tested vitamin K2 in the effective all-trans-menaquinone-7 form (K2VITAL®) to support the transport of calcium from the blood into the bones

  • Supplemented with boron and silicon for additional support of bone metabolism

  • With 7.5 g premium fish collagen (NATICOL®) per serving

  • Produced with the help of enzymes: optimal absorption in the body

  • Rounded off with biotin, zinc and skin-protecting plant extracts

  • Delicious taste: natural cherry-thyme flavour

  • But also available in a neutral flavour, in the ‘Neutral Edition

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What are phytoestrogens?

These plant-based compounds—found in soy, red clover, and hops—are nature’s own estrogen mimics. They bind to estrogen receptors and can gently support or modulate hormonal activity.

Research suggests they may ease menopause symptoms like hot flashes and night sweats, offering plant-powered balance for women in transition.

Customer favorite: Nutrifem® Agnubalance

Tried, tested, and loved by BIOGENA customers and partners alike, Nutrifem® Agnubalance is our top menopause pick. This smart formula blends wild yam, fennel, hops, soy, and Vitex with vitamins B6 and E—supporting hormonal balance gently and effectively.

Nutrifem Agnubalance®

Nutrifem Agnubalance®

€32.90

Your body is changing—your support should, too. The menopause transition can feel overwhelming, but it’s also a powerful opportunity for self-care. With the right nutrients—like vitamin D, B vitamins, and botanical allies like Vitex and wild yam—you can move through this chapter feeling grounded, supported, and strong.

FAQs

Menopause FAQs – Your top questions answered

References:

Long S.-J., Benton D. 2013. Effects of vitamin and mineral supplementation on stress, mild psychiatric symptoms, and mood in nonclinical samples: a meta-analysis. Psychosom Med. 2013 Feb;75(2):144-53.  doi: 10.1097/PSY.0b013e31827d5fbd. Epub 2013 Jan 29. NCBI - WWW Error Blocked Diagnostic

Bani S. et al. 2013. The effect of folic Acid on menopausal hot flashes: a randomized clinical trial. J Caring Sci. 2013 Jun 1;2(2):131-40.  doi: 10.5681/jcs.2013.016. eCollection 2013 Jun. NCBI - WWW Error Blocked Diagnostic

Sharma M., Kalra S. 2024. Vitamin D and Menopause. J Pak Med Assoc. 2024 Apr;74(4):815-817. doi: 10.47391/JPMA.24-27. NCBI - WWW Error Blocked Diagnostic

Hassanein M.M. et al. 2023. Therapeutic Effects of Vitamin D on Vaginal, Sexual, and Urological Functions in Postmenopausal Women. Nutrients. 2023 Aug 30;15(17):3804. doi: 10.3390/nu15173804. NCBI - WWW Error Blocked Diagnostic

Zhang J. et al. Effects of vitamin D on thyroid autoimmunity markers in Hashimoto's thyroiditis: systematic review and meta-analysis. J Int Med Res. 2021 Dec;49(12):3000605211060675. doi: 10.1177/03000605211060675. NCBI - WWW Error Blocked Diagnostic

Doshi S.B., Agarwal A. 2013. The role of oxidative stress in menopause.
J Midlife Health. 2013 Jul;4(3):140-6. doi: 10.4103/0976-7800.118990. NCBI - WWW Error Blocked Diagnostic

Feduniw S. et al. 2022. The Effect of Vitamin E Supplementation in Postmenopausal Women-A Systematic Review. Nutrients. 2022 Dec 29;15(1):160. doi: 10.3390/nu15010160. NCBI - WWW Error Blocked Diagnostic  

Khalili-Farshbaf A. et al. Clinical Efficacy of Curcumin and Vitamin E on Inflammatory-Oxidative Stress Biomarkers and Primary Symptoms of Menopause in Healthy Postmenopausal Women: A Triple-Blind Randomized Controlled Trial. J Nutr Metab. 2022 Jun 9:2022:6339715. doi: 10.1155/2022/6339715. eCollection 2022. NCBI - WWW Error Blocked Diagnostic

Semwal P. et al. 2022. Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives. Oxid Med Cell Longev. 2022 May 29:2022:1035441.  doi: 10.1155/2022/1035441. eCollection 2022. NCBI - WWW Error Blocked Diagnostic

Song C. et al. 2023. Diosgenin reduces bone loss through the regulation of gut microbiota in ovariectomized rats. Gene. 2023 Jun 15:869:147383.  doi: 10.1016/j.gene.2023.147383. Epub 2023 Mar 29.

Wu F.-C., Jiang J.-G. 2019. Effects of diosgenin and its derivatives on atherosclerosis. Food Funct. 2019 Nov 1;10(11):7022-7036.  doi: 10.1039/c9fo00749k. Epub 2019 Nov 5. NCBI - WWW Error Blocked Diagnostic

Abbaspoor, Z. et al. 2011. Effect of Vitex agnus-castus on Menopausal Early Symptoms in Postmenopausal Women: A Randomized, Double Blind, Placebo-Controlled Study. Br J Med Med Res. 1(3):132–4. https://journaljammr.com/index.php/JAMMR/article/view/808

Van Die M.D. et al. 2009. Vitex agnus-castus (Chaste-Tree/Berry) in the treatment of menopause-related complaints. J Altern Complement Med. 2009 Aug;15(8):853-62.  doi: 10.1089/acm.2008.0447. NCBI - WWW Error Blocked Diagnostic

Asserin, J. et al. 2015. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. J Cosmet Dermatol. 2015 Dec;14(4):291-301. doi: 10.1111/jocd.12174. Epub 2015 Sep 12. NCBI - WWW Error Blocked Diagnostic

Choi, F.D. 2019. Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. J Drugs Dermatol. 2019 Jan 1;18(1):9-16. NCBI - WWW Error Blocked Diagnostic

De Miranda, R.B. et. al. 2021. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. Int J Dermatol. 2021 Dec;60(12):1449-1461. doi: 10.1111/ijd.15518. Epub 2021 Mar 20. NCBI - WWW Error Blocked Diagnostic

Evans, M. et al. 2021. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. Journal of Cosmetic Dermatology. 20(3):825–834. NCBI - WWW Error Blocked Diagnostic

Hsu T-F et al. 2021. Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study. Nutrients. 2021 Jun 28;13(7):2220. NCBI - WWW Error Blocked Diagnostic

Göllner I et al. 2017. Ingestion of an Oral Hyaluronan Solution Improves Skin Hydration, Wrinkle Reduction, Elasticity, and Skin Roughness: Results of a Clinical Study. J Evid Based Complementary Altern Med. 2017 Oct; 22(4): 816–823. NCBI - WWW Error Blocked Diagnostic

Papakonstantinou E et al. 2012. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012 Jul 1; 4(3): 253–258. NCBI - WWW Error Blocked Diagnostic

Schmidbauer C., Hofstätter G., et al. 2020. Biogena Mikronährstoff-Coach. 4. aktualisierte und erweiterte Auflage, 1158 Seiten.

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