The best vitamins and supplement to boost your immune system

from Mag. Margit Weichselbraun
on 05.11.2025
An image showing three Biogena products: Biogena Sports Immunity, Biogena Immun 24/7, and Biogena Junior Multi Bo°13. In the background, a person with a blue hat is standing in nature.

Not every supplement is a sure-fire hit for the immune system. But there are clear signs that indicate whether a product delivers what it promises – or is just full of empty promises. We show you which criteria are important – and announce our test winner.

What makes test winners stand out in terms of strengthening the immune system – the comparison criteria:

1. Ingredients & composition: The core of an immune supplement

Your immune system is highly organised – it scans, reacts, protects and regulates, day after day. In order to perform these tasks reliably, it needs targeted support: micronutrients that act in the right places and support the immune network.

High-quality immune formulas deliver exactly that – sensibly combined, carefully processed and in an optimally bioavailable form.

These vitamins are long-term favourites for the immune system:

The right minerals and trace elements are also essential:

Plant power as a special boost

Mother Nature is a true immune system expert. Traditional plant extracts bring a breath of fresh air to modern micronutrient formulas and provide added variety and naturalness.

These traditional plants have been valued for generations for their supportive role in the immune system:

Gut health – where immune strength comes from

Around 70% of our immune cells are located in the gut – and that's no coincidence, because this is where they are trained, regulated and balanced. So, if you support your gut in a targeted way, you are also doing your immune system a favour.

These components can provide valuable support in this regard:

BIOGENA tip for product selection:

Sometimes more really is more: Combination supplements that combine several immune-relevant nutrients can be particularly effective – especially if they complement each other and thus work together to boost your immune system.

However, if you have a specific deficiency, such as vitamin D or zinc, a targeted nutrient supply can be the key to restoring balance to your immune system.

2. Science as a foundation – for supplements with substance

There is more than just a good idea behind every high-quality supplement. For a proven effect, a solid scientific foundation is required – with active ingredients whose benefits, dosage and interaction have been thoroughly researched and confirmed by studies. This is the only way to create formulations that are based on evidence rather than trends – and thus truly deliver what they promise.

Premium manufacturers such as BIOGENA therefore rely on tested ingredients, research that demonstrates visible effects, and teams of experts who examine and refine every detail.

This is how knowledge translates into effectiveness and precision translates into trust.

3. Quality & manufacturing – where true test winners are created

True test winners are born out of dedication and mindfulness. Quality is not only evident in the capsule, but begins with the selection of pure raw materials, continues with careful processing and lives on in every detail of the manufacturing process.

How to recognise premium quality:

  • Purity. Only what is truly pure is allowed to go into the product. High-quality preparations consistently avoid unnecessary additives, artificial flavours or potential allergens – and are strictly tested for residues such as heavy metals. Because your body deserves only what is good for it.
  • Manufacturing. Quality does not happen by chance, but through clear standards. Certified production processes – such as ISO 22000 certification – ensure that every preparation is manufactured under controlled conditions and according to the highest standards of food safety.
  • Transparency. Another key to true premium quality: traceability and strict quality controls by independent third parties. Top manufacturers disclose where their raw materials come from, how they are processed and what quality tests they undergo. This transparency is not a trend – it is the foundation of true credibility.

4. Compatibility & application: Because well-being begins with feeling good

A true test winner impresses not only with its content, but also in everyday use – with high tolerability and ease of application.

High-quality immune supplements are gentle on the body, free from unnecessary additives and – where possible – vegan. They can be easily integrated into everyday life, whether as capsules, powder or drops – for an immune routine that simply fits.

5. Customer reviews & testimonials: What users say

Genuine quality is not only evident on paper, but also in everyday life – among the people who use a product regularly. Customer reviews and testimonials provide valuable insights into how well an immune supplement actually works and is tolerated.

After all, what good is the best theory if it doesn't work in practice? A true test winner for strengthening the immune system passes both tests – the scientific one and the everyday one.

Our BIOGENA test winner for the immune system for adults

BIOGENA Immun 24/7 is your daily companion for powerful defences – around the clock. The carefully considered formula combines 12 vitamins and 8 minerals that support the body, especially in times of increased stress.

Added to this are selected plant extracts from echinacea, rockrose, eucalyptus and astragalus, supplemented by beta-carotene, quercetin (Quercefit®) and beta-glucans – a powerful combination that harmoniously unites science and nature.

biogena-line
Immune 24/7
Special immune complex with 12 vitamins, 8 minerals and proven plant extracts to support the body's own defences
Buy capsules with vitamins and other supplements for the immune system
€25.90

Our BIOGENA immune system test winner for children

Junior Multi Bo® 13 contains colourful but uncoloured pellets (NutriGellets®) with 13 vitamins as well as iron and iodine – in child-friendly doses for an all-round balanced supply of micronutrients. This provides the body with important nutrients – including those that play a role in the immune system.

Thanks to the protective fish gelatine matrix, the small pearls are easy to take – on their own on a spoon, with water or sprinkled over a meal. For smart micronutrient power that children enjoy and parents trust.

biogena-line
Junior Multi Bo® 13 
Micronutrient pearls with 13 vitamins, iron & iodine - child-friendly consumption without capsule shell possible
To the multivitamins for children
€50.90

Our BIOGENA immune system test winner for athletes

BIOGENA SPORTS Immunity is our test winner for anyone who lives an active lifestyle and wants to give their immune system a targeted boost.

The sophisticated formula combines the best of science and nature: medicinal mushrooms such as reishi, cordyceps and shiitake are combined with plant extracts from turmeric, echinacea, black garlic, elderberry and black peppersupplemented by the classic micronutrients vitamins A, C and D as well as zinc and selenium, which contribute to the normal functioning of the immune system.

The result: a powerful formula that supports you during active phases and reliably strengthens your immune system – for energy, balance and regeneration, even after training.

biogena-line
BIOGENA SPORTS - Immunity 
Premium complex with traditional medicinal mushrooms, valuable plant extracts and the micronutrient classics vitamins A, C, D as well as zinc and selenium to support the immune system for all physically active people
Immune system complex for athletes
€33.90
BIOGENA SPORTS - Immunity - 90 Kapseln

Conclusion

A strong immune system needs more than empty promises – it needs quality, knowledge and trust.

Our BIOGENA test winners demonstrate what modern micronutrient research can achieve: well-founded and carefully considered formulas, pure ingredients and maximum bioavailability – for noticeable support in every phase.

Frequently asked questions about the immune system test winner

Omni Lactis® 20 Gold and Omni Lactis® 20 Pur Gold are our BIOGENA test winners when it comes to supporting the immune system. With 20 billion viable bacteria from 10 scientifically tested strains per daily dose, they support a diverse intestinal flora – and thus maintain your immune headquarters in a natural way.

References:

Balamurugan BS, et al. 2024. Micro nutrients as immunomodulators in the ageing population: a focus on inflammation and autoimmunity. Immun Ageing. 2024 Dec 27;21(1):88. doi: 10.1186/s12979-024-00492-7. PMID: 39731136; PMCID: PMC11674512. https://pubmed.ncbi.nlm.nih.gov/39731136/

Dai X, et al. 2015. Consuming Lentinula edodes (Shiitake) Mushrooms Daily Improves Human Immunity: A Randomized Dietary Intervention in Healthy Young Adults. J Am Coll Nutr. 2015;34(6):478-87. doi: 10.1080/07315724.2014.950391. Epub 2015 Apr 11. PMID: 25866155. https://pubmed.ncbi.nlm.nih.gov/25866155/

Carr A.C., Maggini S. 2017. Vitamin C and Immune Function. Nutrients. 2017 Nov 3;9(11):1211. https://pubmed.ncbi.nlm.nih.gov/29099763/

Van Straten, M., Josling, P. 2002. Preventing the common cold with a vitamin C supplement: a double-blind, placebo-controlled survey. Adv Ther. 19(3):151-9. https://pubmed.ncbi.nlm.nih.gov/12201356/

Heimer, K. A. et al. 2009. Examining the evidence for the use of vitamin C in the prophylaxis and treatment of the common cold. J Am Acad Nurse Pract. 21(5):295–300. doi: 10.1111/j.1745-7599.2009.00409.x. https://pubmed.ncbi.nlm.nih.gov/19432914/

Haase, H., Rink, L. 2009. The immune system and the impact of zinc during aging. Immunity & Ageing. 6:9. doi: 10.1186/1742-4933-6-9. https://pubmed.ncbi.nlm.nih.gov/19523191/

Sunil J Wimalawansa  S.J. 2023. Infections and Autoimmunity-The Immune System and Vitamin D: A Systematic Review. Nutrients. 2023 Sep 2;15(17):3842. doi: 10.3390/nu15173842. https://pubmed.ncbi.nlm.nih.gov/37686873/

Lal A. 2019. Iron in Health and Disease: An Update. Indian J Pediatr. 2019 Sep 13. https://pubmed.ncbi.nlm.nih.gov/31520313/

Biesalski, H. K., Nohr, D. 2004. New aspects in vitamin A metabolism: the role of retinyl esters as systemic and local sources for retinol in mucous epithelia. J Nutr. 134(12 Suppl):3453S-3457S. https://pubmed.ncbi.nlm.nih.gov/15570053/

Ferencik, M., Ebringer, L. 2003. Modulatory effects of selenium and zinc on the immunsystem. Folia Microbiol. 48(3):417-26. doi: 10.1007/BF02931378.
https://pubmed.ncbi.nlm.nih.gov/12879758/

Ross M.S. 2016. Echinacea purpurea: A Proprietary Extract of Echinacea purpurea Is Shown to be Safe and Effective in the Prevention of the Common Cold. Holist Nurs Pract. 2016 Jan-Feb;30(1):54-7. https://pubmed.ncbi.nlm.nih.gov/26633727/

Chainani-Wu N. 2003. Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa) J Altern Complement Med. 2003 Feb;9(1):161-8. https://pubmed.ncbi.nlm.nih.gov/12676044/

Di Pierro F, et al. 2021. Possible Therapeutic Effects of Adjuvant Quercetin Supplementation Against Early-Stage COVID-19 Infection: A Prospective, Randomized, Controlled, and Open-Label Study. Int J Gen Med. 2021 Jun 8;14:2359-2366. doi: 10.2147/IJGM.S318720. PMID: 34135619; PMCID: PMC8197660. https://pubmed.ncbi.nlm.nih.gov/34135619/

Biesalski, 2017. Taschenatlas der Ernährung. Georg Thieme Verlag KG.

Schmidbauer C., Hofstätter G. et.al. 2020. Mikronährstoff-Coach. Das große BIOGENA-Kompendium der Nährstoffe. 4. Aktualisierte und erweiterte Auflage.

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