Micronutrients

Magnesium and potassium: benefits of this powerful duo

from Dr. Michael Kohlberger, BSc, MSc
on 30.07.2025
Two people are sitting by the sea

Potassium and magnesium. You've probably heard of both minerals. They are involved in countless metabolic processes in your body and can therefore have many beneficial effects. But it gets even better: these two vital substances complement each other. In other words, taking magnesium and potassium together gives you a powerful duo that can have a positive effect on many areas of your body, from your heart to your muscles and nervous system. In this blog post, we'll tell you all about the unbeatable interaction between magnesium and potassium and why it makes sense to take both at the same time.

Magnesium: what your body needs the mineral for

Let's first take a closer look at each of these two substances individually. First, there is magnesium, a real powerhouse. Whether it's the nervous system, muscle function, immune system or blood circulation – magnesium plays a role in over 300 bodily functions. Conversely, this also means that a magnesium deficiency can manifest itself in many ways and should not be underestimated.

The most important tasks of magnesium include:

  • Building block for bones and teeth
  • Protection and motor for cells
  • Communicator between muscles and nerves
  • Good mood spreader and relaxation promoter
  • All-round talent for hormone balance
  • Support for the heart
  • Power substance for more energy
More information on magnesium requirements and use

The all-rounder potassium: what tasks does this electrolyte perform?

Let’s now move on to potassium, an important electrolyte that is mostly familiar to athletes. Your body also depends on this substance, because without potassium, many of your internal processes would no longer function smoothly. A potassium deficiency should therefore not be taken lightly.

The most important functions of potassium include:

  • Building block for energy production
  • Guardian of water and acid-base balance
  • Fuel for the heart
  • Helper for the nerves

Magnesium and potassium together: what are the benefits of taking the two together

Both vital substances therefore offer a number of benefits independently of each other – but the real benefits only come into play when you take magnesium and potassium together. This is because the two substances complement each other perfectly. The main beneficiaries of this are:

  • Your cardiovascular system: The remarkable interaction between magnesium and potassium can improve cardiac arrhythmia and harmonise heart activity.
  • Your muscles: If you do a lot of sport, your body needs more nutrients. If you don't give it these, you risk developing a deficiency. This is where potassium and magnesium can help. They have a positive effect on your electrolyte balance and relax your muscles.

But be careful: the interaction between magnesium and potassium also works in reverse. For example, if you are already struggling with a magnesium deficiency, this can exacerbate the symptoms of a potassium deficiency. In addition, high potassium levels can inhibit magnesium absorption, while high magnesium doses can slow down potassium absorption. So caution is advised here!

Good sources of magnesium and potassium

The bottom line is: pay close attention to your magnesium and potassium balance. The best way to do this is to eat a balanced diet:

  • Good sources of magnesium include: nuts such as cashews and almonds, whole grains, spinach, bananas
  • Good sources of potassium include: green vegetables such as kale, broccoli and spinach, potatoes, legumes, whole grains, fruits such as bananas, honeydew melon and currants, mushrooms, dairy products, oatmeal, cocoa beans and nuts

However, although there are some foods that contain high levels of magnesium and potassium, it can still be difficult to meet your daily requirements. Experts recommend between 400 and 420 mg of magnesium for men and 310 to 320 mg for women per day. They also recommend 4000 mg of potassium daily. Therefore, feel free to use high-quality dietary supplements to support your intake.

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Conclusion: Two that go well together

Magnesium and potassium are essential for your body – each substance has numerous benefits on its own. But you will only really feel the benefits of this powerful duo when you combine them. Both your heart and your muscles will thank you for it. So make sure you eat a balanced diet and feel free to take dietary supplements to meet your needs.

Frequently asked questions about taking magnesium and potassium together

In sensitive individuals, magnesium can lead to loose stools if taken in excessive doses. Other gastrointestinal complaints such as nausea may also occur. In many cases, it is sufficient to switch to the particularly well-tolerated form of magnesium bisglycinate. In rare cases of severe overdose or existing medical diagnoses, magnesium can also affect the circulatory system.

Especially in the last trimester of pregnancy, the combination of higher doses of magnesium and potassium should be used with caution. The reason for this is that both active ingredients have a muscle-relaxing effect, which can inhibit contractions. During the rest of the pregnancy, however, and especially at the beginning, magnesium and potassium can usually be taken without hesitation.

If you have a medical diagnosis and/or are taking medication, you should definitely consult a doctor. Particularly in the case of kidney disease or certain medications, such as potassium-sparing diuretics, care must be taken to avoid any interactions.

There is no universal rule as to whether magnesium and potassium should be taken together in the morning or evening. This depends primarily on individual preferences and needs, as well as the dosage form of the preparation. Some people prefer to take it in the evening to benefit from the muscle-relaxing effect of magnesium shortly before bedtime.

The combination can contribute to normal muscle and nerve function, regulate blood pressure, support muscle contraction, strengthen the cardiovascular system and promote electrolyte balance.

Yes, taking magnesium and potassium at the same time is generally safe and can even be beneficial. Both minerals work closely together and can have a positive effect on electrolyte balance, the cardiovascular system, the nervous system and muscle function.

Sources:

Grover N. On using magnesium and potassium ions in RNA experiments. Methods Mol Biol. 2015;1206:157-63. doi: 10.1007/978-1-4939-1369-5_14. PMID: 25240895. https://pubmed.ncbi.nlm.nih.gov/25240895/

Houston MC, Harper KJ. Potassium, magnesium, and calcium: their role in both the cause and treatment of hypertension. J Clin Hypertens (Greenwich). 2008 Jul;10(7 Suppl 2):3-11. doi: 10.1111/j.1751-7176.2008.08575.x. PMID: 18607145; PMCID: PMC8109864. https://pubmed.ncbi.nlm.nih.gov/18607145/

Khalid S, Mehboob R, Bokhari SS, Ali M, Shabbir A, Mehboob K, Adnan H, Karami MM, Shalabi H, Alshehri B. Comparative Efficacy of Magnesium and Potassium Towards Cholesterol and Quality of Life in Patients With Type 2 Diabetes Mellitus: A Randomised Single-Blinded Controlled Clinical Trial. Endocrinol Diabetes Metab. 2024 Nov;7(6):e511. doi: 10.1002/edm2.511. PMID: 39410716; PMCID: PMC11480119. https://pubmed.ncbi.nlm.nih.gov/39410716/

Pogozheva AV, Kodentsova VM, Sharafetdinov KK. [The role of magnesium and potassium in preventive and therapeutic nutrition]. Vopr Pitan. 2022;91(5):29-42. Russian. doi: 10.33029/0042-8833-2022-91-5-29-42. Epub 2022 Aug 30. PMID: 36394927. https://pubmed.ncbi.nlm.nih.gov/36394927/

Behers BJ, Behers BM, Stephenson-Moe CA, Vargas IA, Meng Z, Thompson AJ, Melchor J, Wojtas CN, Rosario MA, Baker JF, Deevers AC, Mouratidis RW, Sweeney MJ. Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length. Nutrients. 2024 Oct 24;16(21):3617. doi: 10.3390/nu16213617. PMID: 39519450; PMCID: PMC11547496. https://pubmed.ncbi.nlm.nih.gov/39519450/

Beyer FR, Dickinson HO, Nicolson DJ, Ford GA, Mason J. Combined calcium, magnesium and potassium supplementation for the management of primary hypertension in adults. Cochrane Database Syst Rev. 2006 Jul 19;(3):CD004805. doi: 10.1002/14651858.CD004805.pub2. PMID: 16856060. https://pubmed.ncbi.nlm.nih.gov/16856060/

Ryan MP. Interrelationships of magnesium and potassium homeostasis. Miner Electrolyte Metab. 1993;19(4-5):290-5. PMID: 8264516. https://pubmed.ncbi.nlm.nih.gov/8264516/

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