Growing old, staying young: While people once cherished the dream of the source of eternal youth, scientists are now intensively researching how to decipher ageing in order to conquer the natural course of things.


Over time - depending on our genes and other influencing factors - our bodily functions begin to falter - inevitably, so far.

Spermidine, the fountain of youth

With the discovery of the natural cellulose spermidine, science has taken a giant step closer to healthy aging. The latest research indicates that spermidine works to counter age-related changes in our cells. This natural anti-aging product keeps our cells fit and is a key ingredient of any healthy aging strategy.

Mit der Zeit – in Abhängigkeit von unseren Genen und anderen Einflussfaktoren – beginnen unsere Körperfunktionen zu straucheln – unweigerlich, bislang.

Buy Spermidine Supplements online at BIOGENA

Spermidine is the trendiest supplement on the shelf right now - so naturally, the market has been flooded with all kinds of spermidine preparations. When choosing your supplement, always consider the best raw materials and top qualityBIOGENA Spermidine products offer pure spermidine of the highest quality, derived from soybeans. They’re 100% vegan and free of unnecessary additives. The standardized premium soybean extract BIOGENA uses guarantees consistent quality and quantities of valuable spermidine in every capsule.

What is spermidine?

Spermidine is a natural product, chemically classed as a polyamine. Detected for the first time in the 1970s, spermidine owes its name to its origins: it was found in seminal fluid. But don’t be fooled, or even put off by this. We have since discovered that this precious vital substance is not solely reserved for men, but can be found in all living creatures and cells all over the body. Spermidine even appears in plant-based foods such as mushrooms and legumes, albeit in smaller quantities.

But what does spermidine do? Associated with cell growth and cell function, spermidine keeps our cells fresh and healthy by stimulating the cellular self-cleaning process. The older we become, the less spermidine is available in our cells. At the same time, our cell vitality decreases, resulting in an increased risk of age-related illnesses such as cardiovascular disease and dementia. Researchers in the field believe spermidine can potentially arrest the natural process of cellular aging and combat age-related illnesses.

Where is spermidine produced?

Spermidine is found in every cell of the body. The natural product is not produced by cells themselves but by certain enterobacteria. Around one-third of spermidine is produced within the body while the remaining two-thirds, a significant majority, is absorbed from our food.

Which foods contain spermidine?

Spermidine is found in many different foodstuffs including mushrooms, legumes, matured cheeses, whole grain products, and wheat germ. Soybeans contain particularly high levels of this valuable substance and are therefore used to obtain pure spermidine for dietary supplements. Spermidine supplements have the advantage of containing a controlled quantity of the active ingredient. Natural sources, on the other hand, are subject to a great deal of natural variation. Therefore, a high-quality spermidine supplement is your best choice if you wish to precisely compensate for age-related spermidine decline.

Product-Tip: Spermidin Supersior

Spermidine as a nutritional supplement

Capsules, tablets, effervescent tablets, or liquid? What are the best dosage options?

Spermidine is the focus of current research. Dietary supplements with spermidine are available as capsules, tablets, or loose powder. Capsule products, which are produced according to BIOGENA manufacturing standards, make it possible to dispense with unnecessary additives such as dyes, binding and separating agents, or synthetic coating agents. The ultimate “cell-refresh-effect” combination preparations such as Spermidine CellImmun® contain the natural carotenoid astaxanthin, well-dosed spermidine, and zinc to protect the cells from oxidative stress. Higher dosages can be achieved with monopreparations; we recommend Spermidine Superior capsules with 2.5mg spermidine as a daily dose.

What is the best way to take spermidine?

Daily intake at regular times of the day is recommended to keep the natural spermidine content in the body constant.

Why does spermidine have the effect of revitalizing or prolonging life?

What makes spermidine so special is its effect of promoting the body’s natural process of autophagy, which keeps cells fresh and healthy. Studies have confirmed that spermidine is the “elixir of life”, showing that concentrated quantities of the product combat cellular aging and promote continued cellular health. The underlying mechanism is that of autophagy – but what, exactly, does that mean?

What is autophagy?

Autophagy. The cleanup program for cells

Imagine you have purchased an old, dilapidated house. The roof leaks, the fence is rotten and the plaster walls are disintegrating. Autophagy, in this instance, would be the name of the construction company that helps you to repair and restore the house, removing the decayed sections and repairing and reusing them.

In terms of the body, autophagy functions as a cellular garbage disposal service. This self-cleaning program helps cells by removing everything from damaged or misfolded proteins to entire organelles and then recycling them. This is an important role, as damaged cell materials hurt cell health and can, in severe cases, cause serious harm.

Autophagy – cleaning up the cells:

  • Breaking down damaged or unnecessary cell materials
  • Recycling the components
  • Stimulating cell metabolism

Spermidine studies show that the natural “fountain of youth” significantly increases our healthy lifespan

“Spermidine extends life” – this is the conclusion reached by an international team of scientists based at the Medical University of Innsbruck. To investigate the life-prolonging effects of spermidine, these researchers observed 829 people in a South Tyrolean community over a period of 20 years (aged 45–84 years). 341 participants died during the course of the study, and of these, 40.5% had a low-spermidine diet. By contrast, subjects who enjoyed a high-spermidine diet were 15% less likely to die and lived between 5 and 7 years longer. The study also showed that higher spermidine levels offered protection against vascular, digestive and nervous ailments.

How does intermittent fasting promote the effects of spermidine?

Nature has another way to activate this cell cleanup program: fasting. When nutrition is not provided, cells turn to their “contaminated areas” and begin to recycle them. Numerous studies have proven that a limited supply of nutrition or calories can be beneficial to your health (for example, reducing the risk of diabetes mellitus type 2 or cardiovascular ailments).

Intermittent fasting can be easily implemented in your daily life. This type of fasting is ideal for people who do not want be always hungry or forever counting calories. The rule of thumb is 16:18. That is, 16 hours of fasting to 8 hours of eating. To intensify the health benefits of fasting, or if it’s difficult for you to fit regular fasting into your life, then spermidine is your best option. This substance, which occurs naturally in the body, imitates the effects of fasting by stimulating autophagy.

How does spermidine affect the immune system?

It’s not just our skin that ages over the years, the immune system also gradually becomes “decrepit”. It weakens and becomes more vulnerable to infection. Studies indicate that spermidine can help to stimulate an aging immune system. An international team of researchers has discovered that a regular supply of spermidine is very helpful in bringing immune functions back up to speed.

Even more to the point, a current study by virologists at the Berliner Charité is exploring the potential of spermidine in connection with the highly charged topic of COVID-19. We know from previous research that the coronavirus changes the entire cell metabolism, resulting in a sharp decline in spermidine levels, among other effects. This in turn inhibits the process of cellular waste disposal (autophagy). In the German study mentioned above, cells infected with coronavirus were treated with spermidine, with the result that the virus multiplication rate decreased by around 85%. An earlier study by Professor Simon of Oxford also indicated that spermidine strengthens the immune system’s antiviral responses. So spermidine has two aces up its sleeve when it comes to fighting coronavirus: (a) restricting virus propagation and (b) strengthening the antiviral immune response. But we still have to wait and see – detailed clinical studies will be required before we can draw any definite conclusions.

The upshot

“Getting old is not for the faint of heart”, said Hollywood actress Mae West. But there’s no use getting gray hairs fretting about the natural course of events; after all, studies show that we are at our happiest between the ages of 58 and 77. If you are to get the most out of your “golden years”, you need to age chronologically while remaining young biologically. Spermidine gives you the means to do just that.

Seals of Quality